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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fef8d359a844a37e4853b01bc7f83c94e5334bd1b6f0bb3c4cd1306d6c26b573' 
  AND token = 'GdqxRqBVTVp581+QuCbFCNNVcloIQpkdIcOA4e/ya2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}