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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a58494557cf1be6eb44eb64562387da16350099ecefebe8185c179acb04c59cd' 
  AND token = 'ZKqAkp1fPC3sU0tXATRhb1G2rIgTTnA3SUn22xeWgcQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}