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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74f81ad1301285650d7f35bef8e082f0d099b07410a2d753aeae441b5c0d8216' 
  AND token = 'F5q97w/0zQ5Pu5YpY3C68bvRewRttA91I1m4fRDFSQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}