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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2df9e1421c8621f63ac231e1af7060781021775096d9d56c6ed48d89ceba0059' 
  AND token = 'SDQb+m+vr8+Qgg6WoutQMA23g9WsSw3ZcZH7jXT4JxY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}