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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6232c4d8a147ca7c4de1bc300fb37489b9d0a36df2986576281ada16aabe262b' 
  AND token = 'sxlJrHQiTx7vdPv29LoCQwRW2tzBO85D7Nfz0+Z1dRk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}