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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8b36ff56835925f5165af07e15c878e21fc49c2bd6057437383a22c9951f3eb' 
  AND token = 'PNX58jhu+Wa1q3VpfxPRxVfVIWvVYfpz2N0gssfjl0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}