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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b82d62f4a4e2b58aecc3d941194bf0efab76e95932823a62a75e2a66de6fd1a1' 
  AND token = 'SrPpC8Jz2Kclb4lPocYmoAoeqR67LgSJDIMigL2Oxgw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}