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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c916d7dfd2c5822bde2e75d93be6f30afb69ec9e27503932a85d36d3fccf8833' 
  AND token = '2AU5UL1Gf0tPM9Zmy6WugLKCz606UgzoD16LkyxWZRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}