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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a356b2143047df00e41cab262590ec6b71a7e127bae6eb5a9fe812c05f56034' 
  AND token = '8SN1Wzj5Ie0noYt+1sQ3g2IGCySRJJ4ueQhW1BWqBuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}