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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d6c550c305d993e19468e7bd3e9e58d549a7f52c65dfbf2847370a8ae34e39e' 
  AND token = '46hgpGTpyIpK4yXI5HU7n9sTFmJlKMm9FCrXy3UYDws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}