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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35d3f03aac4acc7b09c1e1163fcdfc69520dd95c82344ca584a38596ad2a426c' 
  AND token = 'BmBy48a069R4F6Rx+4IZErTuQsW3lOyXOsQ3ZeZ8oeQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}