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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57639bd22fb1ef6b57c27fbbe7285dae615f04f4571cc62edabef8e8bdf9e46a' 
  AND token = 'YAi/vNiAoabolIw8H0qXdbsBvJyICmogFZf1hD/cVqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}