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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a76ae223d27030102125a5ee907e3d898e7e5f0f3b52ba3be5116a38a0e9562c' 
  AND token = 'Ygw1aYNINDRnTE9AIU5Azr2CgKgMrK57iCLFVtFCM9o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}