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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7518cdebf742fbe2230bed0e859d4c325abfc6817a2053212f2e874abaa5ce1f' 
  AND token = 'YlSUxkqW1L0Ths+rWJ1tbP+Y4Bo6ZtluHGjlGTRbMcE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}