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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b7b5898e1947bd9ce92c7ebd4d2d3306aee37c9e8519d38e476287c1bf05f87' 
  AND token = 'WHnViSmgiEEz2Mcq4NlMelNlW6kvnnfWPxX2VfFOJhM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}