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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b4e179873e5503d027c9505cf38e12e9b2ff25ec027e0971216e4cafd1c5ec2' 
  AND token = 'pXTgWDTTZedVKhNCsj34/IEv4h1UZK7b6vCGQ4httek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}