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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d43e43596389ff3a0bece13d004f39212e7563d2e93274c9254c2eb4de825ab' 
  AND token = 'A3lUBP9wNpXiNWOryhs91UPQ/OBMa8HOV6aygnSmej4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}