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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd55fbfa885dec39261ba2b5b3ac4ccde8cbcb94283280a500bde8e22266f477' 
  AND token = 'Y0oTwpuRth1pHUTFCTjs6qy3rnTMjt0CP8CB+GXtLJM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}