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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1a92cc56c63c74d42f91935ddd375072d231e1bb260b8728b3228d12008e568' 
  AND token = 'FWC7PCvCWSH8/42gzySRkXNFhozMCXUDqEhQAtac6dU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}