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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bf00e1b3b7737b477817cc4bf5144847a367ccedf5873ed27857c44c5a10546' 
  AND token = 'i7n17rgRxdNZlmu8j9ELwasAadRTdBY7ruFC0JTzQAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}