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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a2dee6a4fdf42d016fc781a74d415fd56a9c6443f0c891af3d190fc1208796a' 
  AND token = 'N1tDsDJWdq9Z0+XxrtsUEeutv+Nur4I3o1XZ79Zxqa0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}