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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5a1620bc561bae204e22c1b7e4bb6315affe462a48cd09dfb42109e7a04137c' 
  AND token = 'TxnAUEvCWcm0LoTlc2TxuX3HPg2/g/wEiJiC2C4GlzM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}