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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43938a68514586d3cb81be7882e426b4115d3751b7a24e6a3b891b8c0d105885' 
  AND token = 'MUH5oHbR6thOUQPa+zo3dBr5I84k85GgxQycoAoO7S0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}