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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95f037deb0ea9421f5302bb68f66a945cbc7377fb828ef57385dce0ad4ae5087' 
  AND token = 'HGm2merwwxdxmDwtjA43OFPKPhFoods8+NEBz0sVYZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}