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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7784120a41daf09987b116cb194f5189a34ff779972f71314b63fadf0357a144' 
  AND token = 'BlpQpv86A7iCtmB2626mS8DnoCo+QlwdLdC0lTln2Zs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}