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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da95f05f735c44b176d4ea0ae11227a1201cc647b556bacfbd3be02f0011129a' 
  AND token = 'I6DzhpI5m4deM9EcT9OrgKLIslkO/JgJduBtv18q6JY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}