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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72093b779a6c8ce5dc636f87ad62c65e073e165d40cb0e4f657bc7af6a23f760' 
  AND token = 'MR2iV9NWXaIa6aWU9tRJvR/okStkoHEaYVPXO0NiUk4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}