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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0664ff39bb52a179e109aeae947bce0a7ef745b1f9555cad525ea6c944e8e2e' 
  AND token = 'nnxWPO6WpCRpcUbTMxY8XLYVzR4W3ckkbIRgubXXlz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}