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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78b6aa052e45e64dd39b0a60ff0e691f0d9323cb44b37c3be24b9310381ea284' 
  AND token = 'gRrrniwsOsUobS44ST5j8kdVKNO3+mdh46QzB8whUVw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}