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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4e6218a2800219892d9e3830620affc0b02604dcf4d6ba25f337a3dc8da55d6' 
  AND token = 'PXHuQhhIU4dEWjWGl/e3pupHl08eqiCYjsphvdmQI9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}