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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a9aaf50104d570f25f91e2aa012c5580e8e46e0012d517b53904ac6dec51005' 
  AND token = '/3/8pKZ2IJ6lNJY9e5prht/jef7HtkovnQg6RhvJnXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}