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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a8c8521e8217622bb36bd0496404aa20e1ab014a7d7e3f1946904e462afb83e' 
  AND token = '1gFo2zLNR/DXiS/DblTehUuSTEkDKSdgDZ3Iwm5WAJY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}