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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2352478c3d5e814186637aa420a0cde40ba8869b1956ccd2ca005da5c93de31' 
  AND token = '4KadFThUpHisrYcMaUXoTZtin99yHScZ48OZCqwtyNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}