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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8124254b9e6e2397b60195c6dc55c02463785dc3e1cc2a3d6af38ca362224d85' 
  AND token = '9QdOMlDcXCEK32JfOV5rGeV01rpYqmha/vkXgyg0VI4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}