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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1c0dc4f31b9a449ae867693339936a94c796c6441991d93d4c00d9edd55abf0' 
  AND token = 'zwVX3uf+8BwxvwfkJe38nxGScWN7GhLFrVGZ13G2UG8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}