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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73f8a5a0e54c0a543d41cc253b2fc748d450f521cdfe93a2a78f47d63301d9ab' 
  AND token = '7Ogog71/DrtbGWAzSR/qmdq2NE4GndkRa3fRL7VWU+k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}