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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22e75a3d2c4d9d3c3ce898dcf8790dec3d5a85a7350d9dca038922856fcb0558' 
  AND token = 'IhNxWnvuz9R6hBU1zl5Wbmu+eCvFq1ohXAa5KI3qZ9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}