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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '514b10a60d0f2d8bd6193afa4d497350fbf62f9d59ecd2c29d8a4178074ca0e6' 
  AND token = 'Vtv6iGCxkaCr5JSxKaO5ACRsOjE95VbNJ1NsNepp9mE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}