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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9012b86b203f4b1c0bcfbfa53e3641b9b26ea5a0400b7f3319555151cc8730ac' 
  AND token = 'fKrBuSgxtsQH4iY/Ag9KAb282xH1Ytrij3Xk2moTWHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}