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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4f5ff2bfcec7aa5fbe7322a997b6bfaccd5a296bc5a1541fbe1ef290e4b3af0' 
  AND token = 'VSmaFlRgDOGFY5KJ0f8dP8Ex9v/Q/2FGWwRy8Syd6Ks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}