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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfc48e957db1beb91d8bd03c66d53b55d3703f3340cb4fcd0ade2ef24e0fc80d' 
  AND token = '2Bk/MxTkeAwapnklx+aSn7x5vuRR95z0cxiHDT2HsGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}