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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e53f300aa82ef0eef6d200ebfa59ba7fd30bbfd747e200d64687e1dbe483fc51' 
  AND token = 'cS86Q/XyxTKrogoHvzcfrmzBdzGqh2YRPTMJ9x/w3KQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}