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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ee8633eb9ebd6e1e0e574c2e148e5ff598e9048c09862b0b1bb8801d455c4f6' 
  AND token = 'KR8J+9/nmE2pK3KYEVDST7xvQdoSsUvdqiuWPcA47d4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}