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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '404c00a5d01848385bbcffd501f12098bc6bc0072626b980a32d2bee527b3802' 
  AND token = 'b5rP4FxVknCbQE74Kv+zL0cs7Za4CfKRO72WdkFeJ8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}