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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '912412ca26ce0f8fd9e681aa31d05459e1360a1c3f052bb307733a2150a72c11' 
  AND token = 'DTXG6lZjH+IjmTg21Ka8h556i+4Up7dPdEJd3cnY7jI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}