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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c246bff66d93f4eda7736e1de1af9183ee2c359a1fd0845cf5c5f67ec723295' 
  AND token = '01MsyZLW/7iAoPu9ozqoFxUOlc6q0nxwPHIa3R7Y+5c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}