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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8262e53febd874d7dae944bde13fd3c45b6889a8a1307f6bb01edef72941d71b' 
  AND token = 'zcrZ7LTLg0ivhR0fqFa+jMLJgXCjwmi2HEEuvh4aai0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}