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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0180cf6a3e8ee2903600d2b6b619bd34a8fbce35f3daf832b8189108a0571408' 
  AND token = 'OsXybqe+UbO4Uu1f6aEEhIepwEuW6L96HUmKOXOiJi8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}