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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '155da12c0d384633a2531e381cda3f75d61cecd5851898a0f40970ba0397a4e4' 
  AND token = 'zg1x4CgCuf/OOHm1fAy7iEZt9Vo2yIO4l7hYr+NsegA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}