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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f59b577c49655c44b4c49ac4cae736a6b3cfd2ab2591dea6902da25750fb597' 
  AND token = 'choG+P9fOJMj5qjQaF1j4RxKBC9vyiVYle0rF5ou2QQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}